Postdoctoral Research Fellow position at Imperial College London

 

We are seeking an outstanding structural biologist to contribute to an ongoing drug discovery project in the groups of Dr Ernesto Cota (Department of Life Sciences) and Prof Edward Tate (Department of Chemistry), funded by Cancer Research UK. This project focuses on structure-guided design of ligands against small GTPases, a validated but challenging set of targets. The project is supported by collaborations with structural, cell biologists, medicinal chemists at Imperial and the CRUK Beatson Institute (Glasgow).

 

Our research is backed by a robust combination of biophysical, biochemical and cellular assays. You will be expected to take a leading role in fragment-based screening, in silico design, protein X-ray crystallography, protein- and ligand-based NMR, and biophysical (ITC, SPR, MST) and biochemical assays, integrating data generated by colleagues working on hit optimisation and hit-to-lead programmes using medicinal chemistry approaches.

 

For further information, please click this link

 

Best wishes,

Ernesto

 

 

Dr Ernesto Cota

Senior Lecturer

 

Imperial College London

Department of Life Sciences

Room 601, Sir Ernst Chain (Biochemistry) Building

Exhibition Rd., South Kensington

London SW7 2AZ