3 DOF doesn¹t even allow you to rotate the brain.

If you want accurate registration of the cortex without changing brain
shape, I¹d look into surface-based registrations.  Surface-based
registrations achieve correspondence across vertices on a standard mesh
(i.e. vertex #1000 in neuroanatomically corresponding locations across
subjects) while maintaining the original shape of the subjects surface in
3D.

Peace,

Matt.

On 7/29/18, 10:40 AM, "FSL - FMRIB's Software Library on behalf of AYS"

<[log in to unmask] on behalf of [log in to unmask]> wrote:

>Hi everyone,
>
>I was wondering if anyone can help me with a registration issue.
>I ran MELODIC, and as a result I got a 1)MELODIC_IC (20 IC concatenated)
>and 2)functional data that are registered onto standard space (300
>subjects, each with visit 1, 2 and 3).
>
>Many of the funcitonal epi images are registered to the standard space in
>a way where the functional data is not fitting onto the red mask
>(standard space MNI152).  The functional data is obviously "bleeding out"
>of the red line (standard mask), which indicates to me that it was poorly
>registered.  I was wondering if there is any way I can make this
>registration more accurate?
>
>I have not inputted any structural data, and I selected 3DOF as my cost
>function.
>
>I'm not sure if it would be correct to increase the the number of degrees
>of freedom.  I read on one of the documentations that if it is between
>subjects, one should select a 12 DOF.  But my only worry is that it would
>warp the head into a different shape and I would lose the natural brain
>shape.
>
>Also, I was wondering if the fact that I didn't input structural data may
>have a role to play in this poorly registered data?
>
>Please let me know what your thoughts are.
>Thanks for your time.
>

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