The Institute of Structural and Molecular Biology (ISMB) is a world-leading interdisciplinary institute in the field of structural, molecular and mechanistic biology, and an important strategic collaboration between UCL and Birkbeck, University of London. Research interests cover a broad range of key research questions in fundamental biology, with a particular focus on the mechanisms of molecular machines. Our approaches are at the cutting edge of interdisciplinary biomolecular science. World-class research facilities are accessible to all ISMB members, including laboratories for cryo-electron microscopy, X-ray crystallography, NMR spectroscopy, biophysical methods, mass spectrometry, computational biology, cell biology, optical microscopy and microbiology. ISMB seminars, symposia and retreats facilitate collaborative research activities, while our PhD programmes, including an ISMB Wellcome Trust funded programme, support recruitment of high-calibre students committed to interdisciplinary research.  The successful candidate will have a world-class record of research in a complementary area, a shared commitment to multidisciplinary and multiscalar approaches to mechanistic biology, and a vision to lead the ISMB to the next stage of its development.