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Dear FSL experts I just ran tbss_1 and tbss_2_reg without problems But when I run tbss_3 I get this error message ++ WARNING: nifti_read_buffer(d2_1110_FA_FA_to_target.nii.gz): data bytes needed = 28884128 data bytes input = 7227325 number missing = 21656803 (set to 0) ++ WARNING: nifti_read_buffer(d2_1113_FA_FA_to_target.nii.gz): data bytes needed = 28884128 data bytes input = 5911697 number missing = 22972431 (set to 0) ++ WARNING: nifti_read_buffer(d2_1120_FA_FA_to_target.nii.gz): data bytes needed = 28884128 data bytes input = 7546218 number missing = 21337910 (set to 0) ++ WARNING: nifti_read_buffer(d2_1126_FA_FA_to_target.nii.gz): data bytes needed = 28884128 data bytes input = 8654353 number missing = 20229775 (set to 0) ** ERROR (nifti_image_read): short header read 'd2_1142_FA_FA_to_target.nii.gz' ** ERROR: nifti_image_open(d2_1142_FA_FA_to_target): bad header info ERROR: failed to open file d2_1142_FA_FA_to_target Image Exception : #22 :: ERROR: Could not open image d2_1142_FA_FA_to_target terminate called after throwing an instance of 'RBD_COMMON::BaseException' I have 501 images in my sample. What is the problem that causes tbss_3 to crash? Best regards Knut Jørgen Bjuland, PhD