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The mutation confirmation would be of interest. I suspect the rise is AFP is a response to compensate for lack of hormone albumin binding. Thus the "free to bound" ratio favouring free in this case. Further examples would expect similar response in testosterone and on estrogens On Thu., 24 May 2018, 10:01 am Jonathan Kay, <[log in to unmask]> wrote: > Any dyslipidemia? > > And are you intending to look for the mutation? > > Jonathan > > On 24 May 2018, at 14:44, horsman graham (R0A) Manchester University NHS > FT <[log in to unmask]> wrote: > > We have a young man recently diagnosed with analbuminaemia who has had his > AFP measured, albeit not for strong clinical indications; this was found > to be raised at 97 IU/mL. Imaging has subsequently shown no cause for this. > Intuitively the association is not surprising but there is little in the > literature in this scenario. Exceptionally rare I know but has anybody else > seen anything similar? > > > > ------ACB discussion List Information-------- This is an open discussion > list for the academic and clinical community working in clinical > biochemistry. Please note, archived messages are public and can be viewed > via the internet. Views expressed are those of the individual and they are > responsible for all message content. ACB Web Site http://www.acb.org.uk > Green Laboratories Work http://www.laboratorymedicine.nhs.uk List > Archives http://www.jiscmail.ac.uk/lists/ACB-CLIN-CHEM-GEN.html List > Instructions (How to leave etc.) http://www.jiscmail.ac.uk/ ------ACB discussion List Information-------- This is an open discussion list for the academic and clinical community working in clinical biochemistry. Please note, archived messages are public and can be viewed via the internet. Views expressed are those of the individual and they are responsible for all message content. ACB Web Site http://www.acb.org.uk Green Laboratories Work http://www.laboratorymedicine.nhs.uk List Archives http://www.jiscmail.ac.uk/lists/ACB-CLIN-CHEM-GEN.html List Instructions (How to leave etc.) http://www.jiscmail.ac.uk/