Assuming that your homology model is that of a dimer, you could put it in a large unit cell (just add CRYST1 record). The only interface you will get from pisa will be your dimer interface.
If your homology model is a monomer, then pisa will not help, of course, and you would need to predict dimerization mode first.
Happy Connecting. Sent from my Sprint Samsung Galaxy S® 5
-------- Original message --------
From: Careina Edgooms <[log in to unmask]>
Date: 3/2/18 6:44 AM (GMT-05:00)
To: [log in to unmask]
Subject: [ccp4bb] validating a homlology model
Dear all
What programs are best used for validate homology models? I know of molprobity but if there are no coordinates I cannot use it. Is there a way to use such programs with homology models?
Also I wish to use pdbepisa for to charaterise dimer interface but again for homology model this cannot be done as there is no PDB model. Does anybody know way to use PISA software on my own model that is not deposited in PDB?
Thank you in advanceCareina
