Dear FSL's team,

I have two experimental groups of patients (A and B). Based on previous findings, I would like to run a Paired One-Group Difference for every group separately. My question is twofold:

1. Is it statistically valid?

2. The model to follow would be this, right? https://fsl.fmrib.ox.ac.uk/fsl/fslwiki/FEAT/UserGuide#Paired_Two-Group_Difference_.28Two-Sample_Paired_T-Test.29).

Best regards,

Rosalia