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Hi - On 16 February 2018 at 16:36, Wu chen <[log in to unmask]> wrote: > Dear SPM experts, > Dear FSL experts, > > I am trying to design an experiment with two conditions (Aggresive, > Happiness ) In which each trial starts with a fixations cross for one > second , stimulus appears for 2 seconds and then blank white screen for > nearly 10 seconds. > > 1) May i know if the duration after appearance of stimulus is enough to > let BOLD response get back to baseline/normal state? > This should be just about adequate. > > 2) Is/are there any publications related to minimum Inter Trial Interval > needed for event related designs? > Have a look at: http://andysbrainblog.blogspot.co.uk/2012/09/optseq-and-event-related-designs.html http://imaging.mrc-cbu.cam.ac.uk/imaging/DesignEfficiency > 3) Is there a thumb rule to follow for the "period " following the offset > of stimulus and beginning of the next TRIAL? > > 4) May I know if the duration of Stimulus is enough for the BOLD response > to occur? > Your duration is typical, but you really need to pilot the paradigm to be certain - it will be very dependent on the specific stimulus I think. Best Eugene > 5) Is/are there any publications related to minimum stimulus duration > needed for BOLD response to occur? > > 6) Is there any common guideline available which can be followed in order > not to make same mistakes again? > > > I would be really thankful to you and appreciate all your efforts. > > Many thanks > Best, Wu > >