"The way in which prior odds might shape our views can be understood when imagining an upside-down world in which randomised trials would be started with the same prior odds of truth as individual SNPs in a genome-wide analysis, say, one in 100,000. Suddenly, randomised trials would look abysmally poor: almost all their positive findings would be chance findings, as one in 20 would be significant by conventional testing. In this upside-down world, almost no positive result of any randomised trial would stand the test of time. Imagine further that observational studies would only be started with priors of at least 50–50. When positive, posterior odds would be of the order of 80–20 or more. Their results would stand the test of time, and would have great face credibility. Observational research would suddenly look very good............."
More here:On Thu, Feb 1, 2018 at 10:12 AM, Rakesh Biswas <[log in to unmask]> wrote:Thanks David,Yet is this thread seriously poised to witness an amalgamation of case reports that currently sit at the bottom of the evidence pyramid with systematic reviews that currently sit at the top and convert the EBM pyramid into a spheroid to make healthcare roll for the better?I had a feeling that once we had begun accepting qualitative research into systematic reviews, case reports wouldn't be far behind as they are essentially the earliest form of common sense making qualitative research?best,rbOn Feb 1, 2018 7:22 PM, "David Richard Leslie Cawthorpe" <[log in to unmask]> wrote:Generally, information entering an electronic health record is post hoc and not subject to qualification for entry into the electronic health record. Some forms of electronic health record data, such as lab results and x-rays, etc. are based on instrumentation, yet all such data require some level of interpretation. Debate will likely continue in respect to the quality of data entering case report systematic review, or electronic health record, or both. Given some level of baseline quality at the point of data entry, the rest depends on sample size and reproducibility (reliability) and validity.
DavidVery interesting discussion.
"When case reports genuinely reflect the best available evidence," and every case worth reporting in this world is reported and sorted out through systematic reviews would that be a new research method or would it come close to data mining through electronic health records?
regards,
rb
On Feb 1, 2018 11:12 AM, "Zachary Munn" <[log in to unmask]> wrote:
When case reports genuinely reflect the best available evidence, it may be worthwhile to include these in a systematic review. We have a critical appraisal tool for case reports available here: https://reviewersmanual.joanna
briggs.org/display/MANUAL/Appe ndix+4+Critical+appraisal+chec klist+for+case+reports
We’ve also recently published an article describing the common systematic review types in health and medical sciences that you might find interesting: What kind of systematic review should I conduct? A proposed typology and guidance for systematic reviewers in the medical and health sciences
Any feedback, critique or advice is welcome, as always.
Kind Regards,
Zac
Assoc Prof Zachary Munn
Director Transfer Science
Director JBI Adelaide GRADE Center
The Joanna Briggs Institute
The University of AdelaideT: +61 8 8313 3642
W: www.joannabriggs.org | http://grade.joannabriggs.org The Joanna Briggs Institute offers a wide range of education and training for clinicians, managers, educators, academics and students from the fields of nursing, allied health, medicine, information science and the health sciences. The JBI Comprehensive Systematic Review Training Program is designed to prepare researchers and clinicians to develop, conduct and report comprehensive systematic reviews of evidence following the Joanna Briggs Institute approach. http://joannabriggs.org/jbi-ed
ucation.html#courses The JBI Clinical Fellowship is a six-month work place, evidence-based, implementation program involving 2 x five-day intensive training workshops in the Joanna Briggs Institute, and a work place evidence implementation project in the intervening months. Participants learn about clinical leadership and how to implement evidence in practice to improve outcomes, with their project report published in our peer reviewed journal, The Joanna Briggs Database of Systematic Reviews and Implementation Reports. http://joannabriggs.org/jbi-ed
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From: Evidence based health (EBH) [mailto:EVIDENCE-BASED-HEALTH@
JISCMAIL.AC.UK ] On Behalf Of Irina Ibraghimova
Sent: Wednesday, 31 January 2018 9:52 PM
To: EVIDENCE-BASED-HEALTH@JISCMAIL.AC.UK
Subject: Re: Systematic reviews of case reports
A typology of reviews: an analysis of 14 review types and
associated methodologies
http://onlinelibrary.wiley.com
/doi/10.1111/j.1471-1842.2009. 00848.x/pdf
Irina Ibraghimova
HealthConnect International
From: Evidence based health (EBH) [mailto:EVIDENCE-BASED-HEALTH@
JISCMAIL.AC.UK ] On Behalf Of Nockels, Keith H.
Sent: 31. siječnja 2018. 10:45
To: EVIDENCE-BASED-HEALTH@JISCMAIL.AC.UK
Subject: Systematic reviews of case reports
Dear All,
I am a health librarian, working with a hospital consultant who wants to do a systematic review. But most, if not all, of the literature on her topic, is reports of a case or of several cases.
My question is: is it possible to conduct a systematic review of case reports?
If you have done this, is there anything special we should know about how to do it? I have increasing experience of working on systematic reviews but not come across this question before.
If there is a more appropriate review type that we should use, I would be interested to have details.
I have found papers that talk about "aggregating case reports” and a “collective analysis” of case reports, but not sure they give details of methods.
Thanks for your help,
Best wishes,
Keith
Keith Nockels MA (Hons) Dip. Lib. MCLIP FHEA
Learning and Teaching Services Librarian (College of Life Sciences)
University Library,
University of Leicester, University Road, Leicester, LE1 7RH, UK
t: +44 (0)116 252 3101
e: [log in to unmask]
w: www.le.ac.uk/library