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Dear Jesper, Thanks you for answering me. With these output files I have not enough information because I can't check outliers before correction and outliers after correction. I can not perform a comparison. I have been designing a Matlab script to get outliers from a DWI volume. Using fslstats with -S and -M options I get volume standard desviation and mean. I consider a voxel as outlier if that voxel has a value higher than mean+2*std or less than mean-2*std. Dou you consider that method is appropiate? Should I change the range [mean-2*std,mean+2*std]? Thanks you very much. I appreciate your opinion. Best, M del Mar