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Hi everyone, Just a quick question. In an "Intention to Treat: a review" by Gupta (2011) ( http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3159210/ ) an intention to treat (ITT) analysis is said to include "all randomized patients in the groups to which they were randomly assigned, regardless of their adherence with the entry criteria, regardless of the treatment they actually received, and regardless of subsequent withdrawal from treatment or deviation from the protocol". In other words, "ITT analysis includes every subject who is randomized according to randomized treatment assignment. It ignores noncompliance, protocol deviations, withdrawal, and anything that happens after randomization." Bearing this in mind, I assume that this means that even if a patient dies during the study (that is, after randomisation), they are still included in an ITT analysis? Thank you for your assistance on this matter. Kind Regards, Kim Dr Kim Pearce PhD, CStat, Fellow HEA Senior Statistician Haematological Sciences Room MG261 Institute of Cellular Medicine William Leech Building Medical School Newcastle University Framlington Place Newcastle upon Tyne NE2 4HH Tel: (0044) (0)191 208 8142 You may leave the list at any time by sending the command SIGNOFF allstat to [log in to unmask], leaving the subject line blank.