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To add to Marko's remark: I believe the main reason for this is the COST function. The affine registration in SPM uses a sum-of-squares COST function, which is less robust than the normalized mutual information (NMI) cost function of the rigid body registration in SPM. 
And: generally it helps to register multiple times, starting with lower degrees of freedom/parameters (e.g. co-registration includes only translations and rotations) before going to more degrees of freedom/parameters (affine = rigid-body + stretching and shearing).

Cheers, Henk

Best wishes/hartelijke groet,

 

 

Henk(-Jan) Mutsaerts, MD PhD

VUmc Amsterdam/AMC Amsterdam/UMCU Utrecht
UMCG Groningen/
Sunnybrook Toronto/RIT NY

Phone: +31 6 4390 8284; Skype: hj.mutsaerts