Hi Matthieu,

Regarding the longitudinal aspect, in PALM compound symmetry has to be assumed. If there are 2 timepoints, this is fine. With more than 2, it becomes progressively more difficult. How many timepoints do you have?

About the 2 modalities, these can be entered in the same call as two separate inputs (two "-i"), and the option "-corrmod" to correct over them, or "-npc" for a joint analysis via NPC.

All the best,

Anderson


On 8 November 2017 at 03:44, Matthieu Vanhoutte <[log in to unmask]> wrote:
Dear Anderson,

Thank you for your answer. My question concerns vertex-wise cortical surface data I have within 2 modalities over time. And I would like to correlate this two modalities across entire cortical surface longitudinally.

Could you indicate me a process or how to do it with PALM ?

Best regards,
Matthieu


2017-11-08 2:41 GMT+00:00 Anderson M. Winkler <[log in to unmask]>:
Hi Matthieu,

Just adding to Niels' answer: for other types of vertexwise data, it's possible to do in PALM (i.e., it will read surface formats such as FreeSurfer's or CIFTI).

All the best,

Anderson

On 7 November 2017 at 15:55, Niels Bergsland <[log in to unmask]> wrote:
Hi Matthieu,
There isn't a direct longitudinal FIRST pipeline, but you can do it.

What you need to do is run the concat_bvars command with all of your data. Then you run first_utils like in the guide. At this point, you need to use fslsplit on the output and then perform the subtractions with fslmaths and then merge the difference images back together with fslmerge. You probably know this already, but the order of the inputs to concat_bvars corresponds to their order in the 4D output from first_utils. So when you do the fslmaths and fslmerge, just make sure that you have things in the right order. 
Good luck!
Niels

On Tue, Nov 7, 2017 at 9:43 PM, Matthieu Vanhoutte <[log in to unmask]> wrote:
Dear FSL's experts,

Do you know if there would be a mean to compare longitudinal evolution of two vertex-wise data (i.e. kind of longitudinal correlation) with PALM or others ?

Best regards,
Matthieu



--
Niels Bergsland
Integration Director / Research Assistant Professor of Neurology
Buffalo Neuroimaging Analysis Center / University at Buffalo
100 High St. Buffalo NY 14203
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