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Hi Matthieu, Regarding the longitudinal aspect, in PALM compound symmetry has to be assumed. If there are 2 timepoints, this is fine. With more than 2, it becomes progressively more difficult. How many timepoints do you have? About the 2 modalities, these can be entered in the same call as two separate inputs (two "-i"), and the option "-corrmod" to correct over them, or "-npc" for a joint analysis via NPC. All the best, Anderson On 8 November 2017 at 03:44, Matthieu Vanhoutte <[log in to unmask] > wrote: > Dear Anderson, > > Thank you for your answer. My question concerns vertex-wise cortical > surface data I have within 2 modalities over time. And I would like to > correlate this two modalities across entire cortical surface longitudinally. > > Could you indicate me a process or how to do it with PALM ? > > Best regards, > Matthieu > > > 2017-11-08 2:41 GMT+00:00 Anderson M. Winkler <[log in to unmask]>: > >> Hi Matthieu, >> >> Just adding to Niels' answer: for other types of vertexwise data, it's >> possible to do in PALM (i.e., it will read surface formats such as >> FreeSurfer's or CIFTI). >> >> All the best, >> >> Anderson >> >> On 7 November 2017 at 15:55, Niels Bergsland <[log in to unmask]> >> wrote: >> >>> Hi Matthieu, >>> There isn't a direct longitudinal FIRST pipeline, but you can do it. >>> >>> What you need to do is run the concat_bvars command with all of your >>> data. Then you run first_utils like in the guide. At this point, you need >>> to use fslsplit on the output and then perform the subtractions with >>> fslmaths and then merge the difference images back together with fslmerge. >>> You probably know this already, but the order of the inputs to concat_bvars >>> corresponds to their order in the 4D output from first_utils. So when you >>> do the fslmaths and fslmerge, just make sure that you have things in the >>> right order. >>> Good luck! >>> Niels >>> >>> On Tue, Nov 7, 2017 at 9:43 PM, Matthieu Vanhoutte < >>> [log in to unmask]> wrote: >>> >>>> Dear FSL's experts, >>>> >>>> Do you know if there would be a mean to compare longitudinal evolution >>>> of two vertex-wise data (i.e. kind of longitudinal correlation) with PALM >>>> or others ? >>>> >>>> Best regards, >>>> Matthieu >>>> >>> >>> >>> >>> -- >>> Niels Bergsland >>> Integration Director / Research Assistant Professor of Neurology >>> Buffalo Neuroimaging Analysis Center / University at Buffalo >>> 100 High St. Buffalo NY 14203 >>> <https://maps.google.com/?q=100+High+St.+Buffalo+NY+14203&entry=gmail&source=g> >>> [log in to unmask] >>> >> >> >