1. Scientific area: Structural Biology, Biochemistry, Chemistry

2. Admission Requirements: The fellowship is dedicated to candidates holding a PhD in chemistry, biochemistry or related areas and experience in structural biology. It is mandatory that the candidate has proven knowhow in protein cloning, expression and purification, crystallization, data collection, structure determination and model refinement. Preference will be given to candidates with experience in different expression systems (bacterial, yeast, insect and mammalian) and biophysical methods for characterizing protein-ligand interactions. The candidate should be able to develop work autonomously. 

3. Work Plan: During the time of the fellowship the candidate will be involved in expression, purification and crystallization of soluble proteins that are important targets for drug development. Biophysical methods will be applied to determine protein-ligand interaction and structure determination will be carried out in the presence of the best hits. Model analysis will allow rationalize the structural determinants that control ligand binding.

4. Rules and Regulations::Law Nr. 40/2004, of 18th August altered and

republish by Decree-Law nº 202/2012 of August 27th (Scientific Research Fellow Statute) and altered by the Decree-Law nº233/2012 of October 29th and by the Law nº12/2013 of January 29th. Regulations for Advanced Training and Qualification of Human Resources, I.P in force (http://www.fct.pt/apoios/bolsas/docs/RegulamentoBolsasFCT2015.pdf).

5. Working location and superviror:  The work is to be carried out at the Departament of Chemistry, at Faculdade de Ciências e Tecnologia da Universidade NOVA de Lisboa (FCT-NOVA) under the scientific supervision of Dr. Teresa Santos-Silva.

6. Fellowship duration: The fellowship will last for 12 months, scheduled to begin in December 2017. The scholarship contract may be renewed during the project.

7. Salary and benefits:  The amount of the fellowship corresponds to € 1.495, according to the table of values ??of grants awarded directly by FCT, I.P. in the country (http: // www.fct.pt/apoios/bolsas/valores), and the payment is made monthly by bank transfer.

8. Selection methodology: The candidates will be evaluated according to their CV (40%) and proven lab experience (60%). In case of a tie, an interview will be requested and the final grade will be defined by the average of the evaluation of the CV (30%), proven lab experience (50%) and interview appreciation (20%). 
9. Jury members: 

            Teresa Santos Silva, PhD and PI of the project – president of the juri

            Professor Maria Joao Romao; Catarina Coelho, PhD – effective juri

            Ana Luisa Carvalho, PhD; Francisco Leisico, MSc – substitute juri

10. Notification of Results: The final results of the evaluation will be publicized through a list sorted by ranking list, posted in a visible and public place of the Department of Chemistry of Faculdade de Ciências e Tecnologia da Universidade NOVA de Lisboa (FCT-NOVA), and all candidates being notified by email.

11. Application Procedure: Application from 21^th of November to 5^th of December of 2017.

Candidates should send by email the following documents in PDF format:

(a)  motivation letter with a synopsis of the CV; 

(b)   Curriculum vitae (up to 4 pages);

(c)  PhD certificate 

(d)  Name and contact of three persons for references

Applications should be sent to: [log in to unmask] with the subject “Application to BPD fellowship –  PTDC/QEQ-MED/1902/2014”.