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Dear all



I'd like to draw your attention to the postdoc position in protein
crystallography, currently open in my group at UCIBIO-NOVA (Faculty of
Science and Technology, NOVA University of Lisbon, Portugal).



I am a young PI interested in protein-ligand interactions for
structural-based drug design and the Postdoc will be integrated into my
research team, currently holding 9 full-time people. The fellowship will be
awarded for a period of 12 months, eventually extended using other funding
schemes.



Candidates should hold a PhD in chemistry, biochemistry or related areas
and experience in structural biology. It is mandatory that the candidate
has proven know-how in protein cloning, expression and purification,
crystallization, data collection, structure determination and model
refinement. Preference will be given to candidates with experience in
different expression systems (bacterial, yeast, insect and mammalian) and
biophysical methods for characterizing protein-ligand interactions. The
candidate should be able to develop work autonomously.



Work Plan: During the time of the fellowship the candidate will be involved
in expression, purification and crystallization of soluble proteins that
are important targets for drug development. Biophysical methods will be
applied to determine protein-ligand interaction and structure determination
will be carried out in the presence of the best hits. Model analysis will
allow rationalize the structural determinants that control ligand binding.



Application deadline is December 5th .

For more information please check the following link:

http://www.eracareers.pt/opportunities/index.aspx?task=global&jobId=94638



I am happy to answer all your questions

Kind regards

teresa
PS: sorry for the earlier mail with wrong subject.

Unique identifier: 1c293f55-6fac-403e-b737-b1faf2575b77

<http://www.eracareers.pt/opportunities/index.aspx?task=showAnuncioOportunities&jobId=94638&idc=1>
*1. Descrição do cargo/posição/bolsa*
*1. Job description*
------------------------------
*Job:*
Research Fellowship for a PhD holder

*Job/Fellowship Reference:* PTDC/QEQ-MED/1902/2014

*Main research field:* Chemistry

*Sub research field:* Biochemistry

*Job summary:*

One fellowship for a PhD holder is opened under the scope of the project
“Carbon monoxide guided shuttles (COGSs) to fight Rheumatoid Arthritis” /
NOVA.ID.FCT – Associação para a Inovação e Desenvolvimento da FCT,
(PTDC/QEQ-MED/1902/2014),  which is financed by national funds from
FCT/MCTES (PIDDAC)

*Job description:*

*1. Scientific area: *Structural Biology, Biochemistry, Chemistry



*2*. *Admission Requirements:* The fellowship is dedicated to candidates
holding a PhD in chemistry, biochemistry or related areas and experience in
structural biology. It is mandatory that the candidate has proven knowhow
in protein cloning, expression and purification, crystallization, data
collection, structure determination and model refinement. Preference will
be given to candidates with experience in different expression systems
(bacterial, yeast, insect and mammalian) and biophysical methods for
characterizing protein-ligand interactions. The candidate should be able to
develop work autonomously.



*3. Work Plan*: During the time of the fellowship the candidate will be
involved in expression, purification and crystallization of soluble
proteins that are important targets for drug development. Biophysical
methods will be applied to determine protein-ligand interaction and
structure determination will be carried out in the presence of the best
hits. Model analysis will allow rationalize the structural determinants
that control ligand binding.



   1. *Rules and Regulations::*Law Nr. 40/2004, of 18th August altered and

republish by Decree-Law nº 202/2012 of August 27th (Scientific Research
Fellow Statute) and altered by the Decree-Law nº233/2012 of October 29th
and by the Law nº12/2013 of January 29th. Regulations for Advanced Training
and Qualification of Human Resources, I.P in force (
http://www.fct.pt/apoios/bolsas/docs/RegulamentoBolsasFCT2015.pdf*).*



   1. *Working location* *and superviror:*  The work is to be carried out
   at the Departament of Chemistry, at Faculdade de Ciências e Tecnologia da
   Universidade NOVA de Lisboa (FCT-NOVA) under the scientific supervision of
   Dr. Teresa Santos-Silva.



   1. *Fellowship duration*: The fellowship will last for 12 months,
   scheduled to begin in December 2017. The scholarship contract may be
   renewed during the project.



   1. *Salary and benefits:  *The amount of the fellowship corresponds to €
   1.495, according to the table of values ??of grants awarded directly by
   FCT, I.P. in the country (http: // www.fct.pt/apoios/bolsas/valores),
   and the payment is made monthly by bank transfer.



   1. *Selection methodology*: The candidates will be evaluated according
   to their CV (40%) and proven lab experience (60%). In case of a tie, an
   interview will be requested and the final grade will be defined by the
   average of the evaluation of the CV (30%), proven lab experience (50%) and
   interview appreciation (20%).
   2. *Jury members: *

            Teresa Santos Silva, PhD and PI of the project – president of
the juri

            Professor Maria Joao Romao; Catarina Coelho, PhD – effective
juri

            Ana Luisa Carvalho, PhD; Francisco Leisico, MSc – substitute
juri

   1. *Notification of Results: *The final results of the evaluation will
   be publicized through a list sorted by ranking list, posted in a visible
   and public place of the Department of Chemistry of Faculdade de Ciências e
   Tecnologia da Universidade NOVA de Lisboa (FCT-NOVA), and all candidates
   being notified by email.

*11. **Application Procedure: *Application from 21th of November to 5th of
December of 2017.

Candidates should send by email the following documents in PDF format:

(a)  motivation letter with a synopsis of the CV;

(b)   Curriculum vitae (up to 4 pages);

(c)  PhD certificate

(d)  Name and contact of three persons for references

Applications should be sent to: [log in to unmask] with the subject
“Application to BPD fellowship –  PTDC/QEQ-MED/1902/2014”.



*Vacant posts:* 1

*Type of contract:* Information not available

*Job country:* Portugal

*Job city:* Caparica

*Job company/institute:* NOVA.id.FCT - Associação para a Inovação e
Desenvolvimento da FCT


*Application deadline:* 05 Dezembro 2017
*(The Application's deadline must be confirmed on the Job Description)*



-- 
Teresa Santos-Silva
Research Assistant Professor
UCIBIO@REQUIMTE
Universidade NOVA de Lisboa
00351-212948300 ext. 10940
http://docentes.fct.unl.pt/tsss/