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I agree with John. Surface Laplacian could give you more interpretable
sensor data. However, with 19 electrodes it's also not ideal.

Vladimir

On Mon, Oct 30, 2017 at 3:20 PM, nasibeh talebi <[log in to unmask]>
wrote:

>
>
> Dear Vladimir
>
> Thanks a lot for your help.
> I will try your comments.
>
> Best regatds.
>
> Nasibeh
>
> On Mon, Oct 30, 2017 at 6:01 PM, Vladimir Litvak
> <[log in to unmask]> wrote:
> Dear Nasibeh,
>
> Connectivity analyses are challenging even with a large number of
> channels. Projecting your data to source space does not get rid of volume
> conduction. I would recommend you to use a minimum norm solution and
> perhaps carefully choose your connectivity measure to, for instance, only
> use the imaginary part of the cross-spectrum.
>
> Best,
>
> Vladimir
>
> On Mon, Oct 30, 2017 at 2:21 PM, nasibeh talebi <[log in to unmask]>
> wrote:
>
> Dear Vladimir
>
> Thanks a lot for your helpful advice. Actually, I am going to perform a
> connectivity study with this dataset, and as the connectivity measures are
> affected by the "volume conduction" effect, I want to extract the
> underlying sources of the scalp potentials.
> I am wondering if I can have your comments.
>
> Best,
>
> Nasibeh
>
>
>
>
> On Monday, October 30, 2017, 5:39:21 PM GMT+3:30, Vladimir Litvak <
> [log in to unmask]> wrote:
>
>
> Dear Nasibeh,
>
> 19 electrodes is indeed a pretty low number. If the spatial solution
> cannot be well estimated then also the time courses will not be separated
> well. If you are just interested in the temporal dynamics it might be
> better to stay at the sensor level.
>
> I don't think using a coarse mesh can change anything in this case, but
> perhaps using IID or COH solution (the latter similar to LORETA) will be
> more robust with a small electrode number than MSP.
>
> Best,
>
> Vladimir
>
> On Mon, Oct 30, 2017 at 1:53 PM, nasibeh talebi <00000a9d20e1b6de-dmarc-
> [log in to unmask] <[log in to unmask]>>
> wrote:
>
> Dear Eugenio
>
> Thanks a lot for your great help. Would you please help me with these two
> question:
>
> 1. The low accuracy problem of the source reconstruction (due to the
> small number of EEG electrodes ) is only related to the spatial
> specification of the sources, or their temporal activity is also poorly
> estimated?
> 2. for a small number of electrodes, is it preferable to use "*coarse *cortical
> mesh" instead of *normal*?
>
> Best regards
> Nasibeh
>
>
>
>
> On Monday, October 30, 2017, 11:56:14 AM GMT+3:30, Eugenio Abela <
> [log in to unmask]> wrote:
>
>
> Source recon from 19 electrode EEG is tricky because of low spatial
> sampling; be careful when interpreting the data.
>
> That being said, your time series looks ok to me - SPM applies a Hanning
> window per default, so the data will have highest amplitude in the middle
> of the trial and be damped towards beginning and end. This can be switched
> off; have a look at the EEG section of the SPM manual
>
> Hope that helps
> - Eu
>
> Am 30.10.2017 um 08:17 schrieb nasibeh talebi <00000a9d20e1b6de-dmarc-
> [log in to unmask] <[log in to unmask]>>:
>
>
> Dear SPM experts
>
>
>
> Hi
>
>
>
> I have a 19-channel *resting state* EEG dataset. The EEG is recorded for
> about 120s at the sampling rate of 128Hz.
>
> I want to perform the 3D source reconstruction and extract the temporal
> activity of the sources. I used the *MSP* algorithm in SPM, but the
> results are strange (attached file).
>
> Does SPM have an appropriate source reconstruction algorithm for resting
> state EEG? or should I choose an alternative toolbox?
>
>
>
> Best regards
>
> Nasibeh
>
> <td5_sourceSample_MSP.tif>
>
>
>
>