Regards,

Pravin

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Location: Heidelberg, Germany 

Staff Category: Postdoctoral Fellow 

Contract Duration: 2 years 

Grading: N/A 

Closing Date: 29 October 2017 

Reference Number: HD_01179 

Job Description 

The European Molecular Biology Laboratory (EMBL) is one of the highest ranked scientific research organisations in the world. The Headquarters Laboratory is located in Heidelberg (Germany), with additional sites in Grenoble (France), Hamburg (Germany), Hinxton near Cambridge (UK), Rome (Italy) and Barcelona (Spain). 

EMBL Heidelberg is looking for a postdoctoral researcher to join the group of Janosch Hennig at the Structural and Computational Biology Unit. The candidate will work collaboratively with other members of the group on a challenging project, involving several members of the TRIM protein family and their involvement in development and disease. We try to understand the connection between ubiquitylation and RNA binding mechanisms by using integrated structural biology methods with a focus on NMR, but combining it with X-ray and small-angle scattering (X-ray and neutron). Structural data will be combined with proteomics and RNA-seq data to identify binding partners, which further enables structural characterization of complexes to ultimately obtain theories about their function in health and disease. The successful candidate is expected to take a strong lead on his/her project and start to develop independent ideas. 

Experience with structural biology methods is required. Experience with NMR and/or X-ray crystallography/small-angle scattering is beneficial as well as lab and theoretical experience with proteinRNA interactions and general molecular biology methods. The candidate should have a good background in computational structural biology tools (e.g. CCPN/4 etc.) and should have an interest in applied structural biology and biology in general. Applicants lacking the above but have qualifications and expertise in RNA biology, biochemistry, proteomics and related are also encouraged to apply. Experience in programming is not required but beneficial. The position requires the ability to work collaboratively as this project is a group effort. Thus, good teamwork and communications skills are expected as well as high motivation. 

Application Instructions 

Please apply online through www.embl.org/jobs Additional Information EMBL is an inclusive, equal opportunity employer offering attractive conditions and benefits appropriate to an international research organisation with a very collegial and family friendly working environment. The remuneration package comprise a competitive salary, a comprehensive pension scheme, medical, educational and other social benefits, as well as financial support for relocation and installation, including your family. 

Please note that appointments on fixed term contracts can be renewed, depending on circumstances at the time of the review.