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The long-wavelength MX beamline I23 at Diamond Light Source has been added to the current Call for Proposals (deadline 1st Oct) for experiments from April 2018. This novel instrument can offer unique opportunities expanding the wavelength range for MX towards and beyond the sulphur K edge (lambda ~ 5 A). Potential applications are: - Native SAD - Use of strong anomalous signal from M-edges to phase large complexes - Location of sulphur or phosphorus atoms in anomalous difference fourier maps to assist model building - Identification of light atoms like chlorine, potassium and calcium in anomalous difference fourier maps above and below the respective edges The complete end station and detector are in vacuum, hence all measured signal is either from the sample, buffer or sample mount. Special thermally conductive sample mounts are required for experiments. We are currently working on the logistics on how to make sample mounts accessible for the experiments and adaptors to allow fast screening on the existing Diamond beamlines. If you are interested, we strongly encourage you to read the beamline paper (https://doi.org/10.1107/S2059798316001078) which describes the instrument. During the extended commissioning phase, we have solved several difficult native phasing problems and identified or confirmed the atom type for (unknown) peaks present in the electron density for various projects. While the sample mounts are different from standard sample holders, we can use adaptors for pre-screening samples at our high-throughput beamlines in Diamond. For further information, please check our beamline home page. http://www.diamond.ac.uk/Beamlines/Mx/I23.html If you are part of an existing Diamond BAG, please request shifts through your BAG proposal, for new users we have put some instructions on the page below: http://www.diamond.ac.uk/Beamlines/Mx/I23/How-to-apply.html Please do not hesitate to get in touch if you have questions regarding potential projects or the application process. Best regards, Armin Armin Wagner Principal Beamline Scientist I23 Long-wavelength MX Diamond Light Source 0044 (0)1235 778560 -- This e-mail and any attachments may contain confidential, copyright and or privileged material, and are for the use of the intended addressee only. If you are not the intended addressee or an authorised recipient of the addressee please notify us of receipt by returning the e-mail and do not use, copy, retain, distribute or disclose the information in or attached to the e-mail. Any opinions expressed within this e-mail are those of the individual and not necessarily of Diamond Light Source Ltd. Diamond Light Source Ltd. cannot guarantee that this e-mail or any attachments are free from viruses and we cannot accept liability for any damage which you may sustain as a result of software viruses which may be transmitted in or with the message. Diamond Light Source Limited (company no. 4375679). Registered in England and Wales with its registered office at Diamond House, Harwell Science and Innovation Campus, Didcot, Oxfordshire, OX11 0DE, United Kingdom