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Hi All Department of Neuroscience, Physiology and Pharmacology UNIVERSITY COLLEGE LONDON We are seeking to appoint a Research Associate to study the molecular basis of co-translational protein folding using NMR spectroscopy. This project applies structural biology together with molecular biology and biophysics to examine the structure, dynamics and folding of nascent polypeptide chains as they are being synthesised on the ribosome. The work will be undertaken at the Department of Structural and Molecular Biology at UCL and Birkbeck College, as part of the Institute of Structural and Molecular Biology (ISMB) (http://www.ismb.lon.ac.uk/ [1]). The ISMB is equipped with state-of-the-art facilities, including excellent NMR facilities (700, 800MHz equipped with cryoprobes) for structural work as well as and biophysics suite to undertake all aspects of the proposed work. Access to ultra-high field NMR spectrometers are also available through our satellite laboratory at the Francis Crick Institute. This Wellcome Trust funded post is funded for one year in the first instance with the possibility for extension. Key Requirements Applicants should have a PhD in biomolecular NMR spectroscopy and have experience in studying large macromolecular complexes. Experience in at least one of the following areas would be highly desirable: molecular biology, recombinant protein production, biochemistry, molecular dynamics simulations or biophysics. A keen interest in protein (mis)folding and/or protein-based interactions is essential. The candidate joining the laboratory will be a highly motivated individual that can work both independently as well as apart of a team. They should also have a desire to develop their work through the supervision of PhD students, work with other group members and with via established collaborations with groups at Centre for Misfolding Diseases at the University of Cambridge (Profs. Chris Dobson and Michele Vendruscolo) and University of Bristol (Prof. Ian Collinson). Full Advert and Job description can be found at HTTPS://ATSV7.WCN.CO.UK/SEARCH_ENGINE/JOBS.CGI?SID=AMNVZGU9MTY2NDQWNYZ2DF90ZW1WBGF0ZT05NJUMB3DUZXI9NTA0MTE3OCZVD25LCNR5CGU9ZMFPCIZICMFUZF9PZD0WJNZHY2ZPCM0UDMFJDGL0BGU9UMVZZWFYY2GGQXNZB2NPYXRLJMPVYL9YZWZFY29KZT0XNJY0NDA3JNBVC3RPBMDFY29KZT0YMJQ [2]= SONIA CHEEDA Staffing Officer UCL Division of Biosciences 1M01 Medical Sciences Building 1st Floor Mezzanine University College London Gower Street, London WC1E 6BT Tel: +44 (0)20 3108 6482 Links: ------ [1] http://www.ismb.lon.ac.uk/ [2] https://atsv7.wcn.co.uk/search_engine/jobs.cgi?SID=amNvZGU9MTY2NDQwNyZ2dF90ZW1wbGF0ZT05NjUmb3duZXI9NTA0MTE3OCZvd25lcnR5cGU9ZmFpciZicmFuZF9pZD0wJnZhY2Zpcm0udmFjdGl0bGU9UmVzZWFyY2ggQXNzb2NpYXRlJmpvYl9yZWZfY29kZT0xNjY0NDA3JnBvc3RpbmdfY29kZT0yMjQ