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you can fit your model chin A over chain B First save chain A only to a new model either in COOT or outside by editing so now you have two Models - one A B C etc , and one only A Calulat SSM. overlap or some such instruction of A over B and change CHAIN ID to X say Now repeat with SSM overlap A to C.. etc At end you can mere A with all copies.. But also maybe better to sort out the true symmetry first. Do you have a suggested Space group or is it really P1? Eleanor On 23 August 2017 at 20:26, Lorenzo Briganti <[log in to unmask]> wrote: > Dear Phenixbb and CCP4bb members, > > > I'm currently refining a structure and facing some problems. It's > originally a tetramer in solution, but I could only solve it in P1 group, > with 8 molecules in the asymmetric unit (two tetramers). One of my chains > is complete, but the others present some significant gaps. I believe I can > use one chain and apply symmetry operations in order to produce a tetramer, > I've heard it is possible using Coot, but I've never done that. Any > suggestions? > > > Best regards, > > > Lorenzo >