Dear Heidi,

FLAIR images usually have poor contrast between GM and WM and thier main application is not the segmentation into these tissue classes but rather the segmentation of lesion. Thus, the tissue contrast might be not sufficient for a reliable segmentation.

Best,

Christian

On Fri, 7 Jul 2017 08:23:17 +0000, Heidi Foo <[log in to unmask]> wrote:

>Dear SPM experts,
>
>I tried to segment FLAIR images using CAT12. However, there was an error
>message saying bad tissue contrast. Is there any way I can get around this
>issue?
>
>Any help is greatly appreciated.
>
>Thanks!
>
>Regards,
>Heidi Foo
>