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Dear Christian, Thank you for your reply and suggestion. Best Regards, Heidi Foo On Sun, 9 Jul 2017 at 4:01 PM, Christian Gaser <[log in to unmask]> wrote: > Dear Heidi, > > FLAIR images usually have poor contrast between GM and WM and thier main > application is not the segmentation into these tissue classes but rather > the segmentation of lesion. Thus, the tissue contrast might be not > sufficient for a reliable segmentation. > > Best, > > Christian > > On Fri, 7 Jul 2017 08:23:17 +0000, Heidi Foo <[log in to unmask]> wrote: > > >Dear SPM experts, > > > >I tried to segment FLAIR images using CAT12. However, there was an error > >message saying bad tissue contrast. Is there any way I can get around this > >issue? > > > >Any help is greatly appreciated. > > > >Thanks! > > > >Regards, > >Heidi Foo > > > > >