Dear Christian,

I have used CAT12 to analyze surface features on patients versus controls.

Surprisingly, I have found in Alzheimer patients a higher sulcal depth in cingulate gyrus/sulcus compared to controls, whereas studies often show that sulcal depth diminish in patients.

1) Would you have an explanation on this ?

2) Considering sulcal depth measure, is there a meaning to consider significant patterns on gyri ?

Thank you for the feedback.

Best regards,

Matthieu