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Hi Marco,

but what's the best way if the first volume is severely distorted by  
motion during the scan? The first realignment step would use a bad volume  
with unpredictable results on the final mean reference. Doing the first  
step with a good reference could be a solution. But how can I do it in SPM?

Cheers,
Bertram

On Tue, 27 Jun 2017 11:00:32 +0200, Marko Wilke  
<[log in to unmask]> wrote:

> Hi Bertram,
>
> in the batch interface, there is actually a setting for this ("Register  
> to first" or "Register to mean"). In the latter case, there will  
> basically be a two step procedure: registering all images to the first,  
> create mean, then register all images to this one. You should also be  
> able to implement this on the command line, passing a 'rtm' flag to  
> spm_realign. In neither case should you have to manually edit the file  
> order to achieve this.
>
> Cheers
> Marko
>
> Bertram Walter wrote:
>> Dear all,
>>
>> I want to use the middle volume of my functional scan as reference scan
>> for realignment in realign & unwarp. In the manual it is mentioned
>>
>> "The first image in the list specified by the user is used as a reference
>> to which all subsequent scans are realigned. The reference scan does not
>> have to the the first chronologically and it may be wise to chose a
>> "representative scan" in this role."
>>
>> My question: How do I have to specify the scans in realign&unwarp?
>>
>> E.g. if I have 10 scans and want to use scan # 5 as reference
>>
>> Option A: When entering 10 scans in the sequence
>> 5 1 2 3 4 6 7 8 9 10
>> I get realignment parameters for 10 volumes
>>
>>    0.0000000e+00  -1.4331259e-14   1.2492012e-14   9.6730144e-19
>> 1.1186837e-16   2.6148260e-17
>>    1.2853422e-01   8.9730393e-02   3.6775770e-02  -9.4771013e-06
>> -3.2223731e-04   1.4239692e-03
>>    4.6301388e-02  -5.0520113e-02  -6.9045253e-02  -6.6616240e-04
>> -2.1641583e-05   5.6118550e-04
>>    4.6174405e-02   7.0661590e-02   8.4805501e-02   3.6093835e-04
>> 3.1108790e-04   8.4482913e-05
>>    2.1246018e-02   1.2126505e-02   2.8272003e-02  -9.6548672e-04
>> -2.1787263e-04   2.5528354e-04
>>    4.2798897e-02   9.4051293e-02   1.7265070e-01  -1.0246176e-03
>> -1.2925461e-04   2.8213895e-04
>>    1.1362071e-02   6.6483921e-03   7.1757735e-02  -8.6840762e-04
>> -1.9301134e-04  -2.7897976e-04
>>    9.8239930e-03   8.1840421e-02   1.2797305e-01   5.9959604e-04
>> 2.9641170e-04  -5.0873017e-04
>>    1.4794704e-02   9.1027866e-02   9.7297841e-02   5.4889707e-04
>> -9.8659697e-05  -5.5278722e-04
>>    9.3970797e-03   1.1272641e-01   1.2209011e-01   3.9738355e-04
>> 5.6547393e-05  -8.0964723e-04
>>
>> The first line refers to scan no 5, right?
>> The resampled nifti contains 10 volumes
>>
>> Option B: When entering 11 scans in the sequence
>> 5 1 2 3 4 5 6 7 8 9 10
>> I get realignment parameters for 11 volumes
>>
>>    0.0000000e+00  -1.4331259e-14   1.2492012e-14   9.6730144e-19
>> 1.1186837e-16   2.6148260e-17
>>    1.2853422e-01   8.9730393e-02   3.6775770e-02  -9.4771013e-06
>> -3.2223731e-04   1.4239692e-03
>>    4.6301388e-02  -5.0520113e-02  -6.9045253e-02  -6.6616240e-04
>> -2.1641583e-05   5.6118550e-04
>>    4.6174405e-02   7.0661590e-02   8.4805501e-02   3.6093835e-04
>> 3.1108790e-04   8.4482913e-05
>>    2.1246018e-02   1.2126505e-02   2.8272003e-02  -9.6548672e-04
>> -2.1787263e-04   2.5528354e-04
>>   -1.1166691e-14  -5.5177401e-15   1.2492012e-14  -5.7451305e-17
>> 2.3912931e-16   2.4868550e-17
>>    4.2798897e-02   9.4051293e-02   1.7265070e-01  -1.0246176e-03
>> -1.2925461e-04   2.8213895e-04
>>    1.1362071e-02   6.6483921e-03   7.1757735e-02  -8.6840762e-04
>> -1.9301134e-04  -2.7897976e-04
>>    9.8239930e-03   8.1840421e-02   1.2797305e-01   5.9959604e-04
>> 2.9641170e-04  -5.0873017e-04
>>    1.4794704e-02   9.1027866e-02   9.7297841e-02   5.4889707e-04
>> -9.8659697e-05  -5.5278722e-04
>>    9.3970797e-03   1.1272641e-01   1.2209011e-01   3.9738355e-04
>> 5.6547393e-05  -8.0964723e-04
>>
>> The first line and the sixth line refer to scan no 5, right?
>> The resampled nifti contains again 10 volumes and differs slightly from
>> the nifti resulting from option A.
>>
>> Which version should be used?
>>
>> Many thanx,
>>
>> Bertram
>>
>


-- 
Dr. Bertram Walter
Bender Institute of Neuroimaging
University of Giessen
Otto-Behaghel-Str. 10H
35394 Giessen
Germany
Phone +49 (641) 99-26307
    or +49 (641) 99-26331 (Secretary)
Fax   +49 (641) 99-26309
www.bion.de