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Hi Katie, if you cleaned your data with fix using the -m option, the contribution of the motion parameters has been already removed and you should not need to correct further. Best, Ludovica — Ludovica Griffanti, PhD Analysis Postdoctoral Research Assistant Wellcome Centre for Integrative Neuroimaging (WIN) Oxford Centre for Functional MRI of the Brain (FMRIB) Nuffield Department of Clinical Neurosciences, University of Oxford John Radcliffe Hospital Oxford, OX3 9DU, UK email: [log in to unmask] > On 16 Jun 2017, at 3:44 pm, Anderson M. Winkler <[log in to unmask]> wrote: > > Hi Katie, > > Is there substantial variability after FIX that can be explained by motion? If yes, include. If not, not necessary. > > All the best, > > Anderson > > On 14 June 2017 at 21:51, Kathryn Cullen <[log in to unmask] <mailto:[log in to unmask]>> wrote: > Dear FSL Gurus, > We are performing seed-based functional connectivity analysis on resting-state data. We are using fsl-fix as part of our preprocesing pipeline. Do you have an opinion on whether we should also apply a motion outlier confound matrix during our FC analysis, given that we have already used fsl-FIX in our preprocessing? > Thanks, Katie Cullen > University of Minnesota >