Hi Francesco,Not really, for the same reason we don't do permutation with fMRI time series.Maybe if the sessions are well far apart from each other, but there is a substantial risk for invalid results.That said, if the data has already been collected, it may well be worth running the analysis and, if the effects are really strong, consider presenting a case report, being open about this limitation.All the best,AndersonOn 9 March 2017 at 20:42, Francesco Sammartino <[log in to unmask]> wrote:HiWould it be theoretically ok to run randomise on a single subject analysis where the subject has been scanned under multiple conditions?I really have only one subject to study with a unique (for the location) brain implant.Thanks