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Hi Shane, Yes, Melodic can be used for GM maps. However, as usually there is only one such map per subject, it won't be possible to do the dual regression. You will need to come up with a different strategy then. All the best, Anderson On 17 February 2017 at 20:08, Shane Schofield < [log in to unmask]> wrote: > Hello FSL experts, > > I am trying to look at grey matter networks in 2 groups, controls and > patients. Then, I want to determine whether the networks are in spatially > distinct locations, and perform correlations with clinical data. > > Can I use the MELODIC toolkit for this purpose? From the FSL website it > looks like it is meant for fMRI data? Any advice on the workflow is greatly > appreciated. > > Thanks. > Shane >