Dear experts, I have some questions about whole brain signals in resting-state fMRI: 1. What is whole brain signals in resting-state fMRI? 2. How to measure the whole brain signals? 3. Is there any study that establishes a neural, metabolic, or electrophysiological basis of the whole brain signals? In particular, the intrinsic brain activity, CBF/CBV? Thank you in advance for any help you can provide. -- Lei Gao, PhD student; ____________________________________________________ Department of Radiology; Zhongnan Hospital of Wuhan University; Wuhan University; Wuchang District, Wuhan City, 430071; Hubei Province, China. Email: [log in to unmask]