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Dear all, We get requests to quantify urinary dysmorphic RBCs in addition to a dipstick and proteinuria analysis using albumin (glomerular marker) and alpha-1-microglobulin (tubular marker). A few rheumatologists and nephrologists "love" dysmorphic RBCs believing in their value in detecting a glomerular origin of (micro)haematuria. In my opinion, quantification of dysmorphic RBCs is highly observer dependent and sensitive to preanalytical issue. I consider to remove it from our panel. What is the extra value one might expect from the dysmorphic RBCs beyond dipstick and proteinuria profiling as outlined above ? Would you think it possible to have a positive finding of dysmorphic (glomerular) urinary RBCs in the absence of a glomerular proteinuria ? Your input will be much appreciated. Best regards, Mike PD Dr. med. Michael Steiner Medical Head Medizinisches Labor Rostock Südring 81 D-18059 Rostock Germany [log in to unmask]<mailto:[log in to unmask]> Priv.-Doz. Dr. med. Michael Steiner Arzt für Laboratoriumsmedizin Ärztlicher Leiter email: <[log in to unmask]> _______________________________ Medizinisches Labor Rostock Labormedizinisches Versorgungszentrum GbR Südring 81 D-18059 Rostock Medizinisches Labor Rostock | Südring 81 | D-18059 Rostock Tel: +49 (0)381 702 2100 | Fax: +49 (0)381 702 2109 | email: [log in to unmask] Diese E-Mail enthält vertrauliche und/oder rechtlich geschützte Informationen. Wenn Sie nicht der richtige Adressat sind oder diese E-Mail irrtümlich erhalten haben, informieren Sie bitte sofort den Absender und vernichten Sie diese Mail. Das unerlaubte Kopieren sowie die unbefugte Weitergabe dieser Mail ist nicht gestattet. This e-mail may contain confidential and/or privileged information. If you are not the intended recipient (or have received this e-mail in error) please notify the sender immediately and destroy this e-mail. Any unauthorised copying, disclosure or distribution of the material in this e-mail is not allowed. ------ACB discussion List Information-------- This is an open discussion list for the academic and clinical community working in clinical biochemistry. Please note, archived messages are public and can be viewed via the internet. Views expressed are those of the individual and they are responsible for all message content. ACB Web Site http://www.acb.org.uk Green Laboratories Work http://www.laboratorymedicine.nhs.uk List Archives http://www.jiscmail.ac.uk/lists/ACB-CLIN-CHEM-GEN.html List Instructions (How to leave etc.) http://www.jiscmail.ac.uk/