Hi Nancy Li,The cope1 has the parameter estimates of the GLM multiplied by the contrast. The thresh_zstat has the test statistic converted to a z-score and thresholded at a certain level of significance.Which to choose depends on what you'd like to do with the data once it has been loaded into Matlab.All the best,AndersonOn 2 December 2016 at 20:58, Nancy Li <[log in to unmask]> wrote:Hello experts,I am running Feat. And I want to transform the data to matlab. Which image in the output of one subject I should pick up to transform: thresh_zstat1.nii.gz or reg_standard/cope1, what difference between these two folder? Looking forward to your help. Thanks a lot!Have good weekedNancy