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Dear Crystallographers,
Although it seems common practice to use just one wavelength/sweep for the refinement of the final model, wouldn’t it make much better sense to merge all wavelengths into one, and refine the final model against that? Especially if it’s
just one crystal, no? Even if some of the sets are collected to lower resolution, they should still improve things. And in addition to the benefits of increased multiplicity, the different wavelengths should cancel some systematic errors as well. Hmm, I wonder.
Jacob Keller
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Jacob Pearson Keller, PhD
Research Scientist
HHMI Janelia Research Campus / Looger lab
Phone: (571)209-4000 x3159
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