Dear colleagues,
At the VIB
Structural Biology Research Center (Vrije Universiteit Brussel /
VIB), we are looking for a highly qualified and motivated
postdoctoral researcher with a strong background in X-ray
crystallography, biochemistry and biophysics and interested in
biochemical and structural studies on proteins and protein
networks involved in neuronal function and dysfunction.
Project
description: Epilepsy is a very common neurological
disorder for which currently available drugs are highly
inefficient and unspecific. In
collaboration with the group of Prof. Patrik Verstreken (VIB
Center for Brain & Disease Research), we are investigating
novel pathways leading to neurological disorders in general
and epilepsy in particular. The current project involves the
detailed functional and structural characterization of
proteins and protein networks involved in these epilepsy
pathways, using an approach of biochemical
and biophysical methods in combination with structural biology
(For background: Fischer et al Nat. Struct. Mol. Biol. 2016). This
research, combined with in
vivo studies, will contribute not only to a detailed
molecular mechanism on the involved proteins, but it will also
pave the way to establishing novel in vivo epilepsy
models and device strategies for medical intervention.
Required
skills and experience:
· Ph.D. in
structural biology
· Experience
in protein expression, purification and characterization
· Experience
in X-ray crystallography, biochemistry and biophysics
· Experience
with protein expression in mammalian systems is an asset
· Good
communication and teamwork skills
Contact: Please
send applications (including CV, research experience, and at
least two names and contact information for references) to: [log in to unmask].
About
SBRC: The VIB
Structural Biology Research Center focuses on the structure
and dynamics of macromolecular complexes in health and
disease. Our multidisciplinary team of about 70 researchers is
housed in new laboratory facilities and combines extensive
expertise in structural biology (state of the art in-house
X-ray crystallography, NMR, SAXS, cryo-EM and atomic force
microscopy), biophysics, enzymology and molecular biology.
Best regards,
Wim
--
Prof. Dr. ir. Wim Versées
Research group Structural Biology Brussels
Faculty of Science and Bioengineering Sciences
Vrije Universiteit Brussel
VIB Structural Biology Research Center
Building E, Room E4.2
Pleinlaan 2, 1050 Brussel
Belgium
Email: [log in to unmask]
