Dear Jan, try this: spm_summarise('image.nii','all',@mean) spm_summarise('image.nii','all',@std) Best regards, Guillaume. On 16/11/16 10:20, jan frielinghaus wrote: > Hello, > > Is it possible to calculate the mean and standard deviation of an > individual image with SPM12? > > best regards, > Jan -- Guillaume Flandin, PhD Wellcome Trust Centre for Neuroimaging University College London 12 Queen Square London WC1N 3BG