Just a gentle reminder that registration will close November 30, 2016.
Giovanna
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On behalf of the School organizers, I would like to remind that registration for the International School of Crystallography 50th Course: Integrative Structural Biology, to be held in Erice (Italy) June 2-11, 2017, is now open. Please see below for details about the Course and how to apply. I hope to see many of you in Erice.
Giovanna Scapin
INTERNATIONAL SCHOOL OF CRYSTALLOGRAPHY
50th Course: INTEGRATIVE STRUCTURAL BIOLOGY
ERICE-SICILY: 2 – 11 JUNE 2017
E.Y. Jones and J.L. Martin (Directors of the Course)
T.L. Blundell (Director of the School)
Sponsored by the: • European Crystallographic Association • International Union of Crystallography
• Italian Ministry of Education, University and Scientific Research • Sicilian Regional Government
PURPOSE OF THE COURSE
Over the last 50 years, crystallography has developed from a method capable of determining the structures of isolated, soluble proteins to one able to provide detailed information on mechanisms of action of integral membrane proteins, whole viruses and the complex nano-machines that are central to cellular function. To discover how biology works researchers are now combining the power of crystallography with multiple other methods, spanning from the atomic to cellular scale, and including revolutionary developments in electron cryo-microscopy and tomography. This Course will celebrate its milestone as the 50th in the crystallography series started by Dorothy Hodgkin by focusing on integration: 1) of different techniques, 2) of molecular and cellular approaches and 3) of the crystallographic community, including diversity. The aim is to provide young researchers with a review of the fundamental approaches and latest developments in the application of crystallography and hybrid methods to the structure and function of biological macromolecules and complexes. Lectures will exemplify use of integrated approaches to analyse molecular mechanism in human and pathogen biology. There will be hands-on workshops to provide practical experience and in-depth
discussion of topics ranging from sample preparation to data analysis software. To commemorate the achievements of the Erice crystallography school over the past 50 years, the course will feature several sessions that reflect on the past and look to the future to highlight the factors that create an inclusive discipline.
APPLICATIONS
Interested candidates should register by 30th November 2016 using the form available in the school website (crystalerice.org).
Applicants may be able to apply for partial financial support. Please visit crystalerice. org to view the full eligibility criteria.
CURRENT LIST OF SPEAKERS AND TOPICS
Nenad Ban (ETH Zurich): Protein synthesis by large cellular assemblies
David Bardford(LMB Cambridge): The anaphase-promoting complex
Pamela Bjorkman (Caltec): Immune recognition of viral pathogens
Tom Blundell (Cambridge University): TBD and “Celebrating the 50th International School of Crystallography”
Bridget Carragher (NYSBC): Intro to Cryo-EM
Wah Chiu (Baylor College of Medicine) Electron cryo-microscopy of biological nanomachines
Elena Conti (MPI for Biochemistry): RNA metabolism
Piet Gros (Utrecht University): The complement system
Sun Hur (Harvard University): Signal transduction by immune receptors
Yvonne Jones (University of Oxford): Cell surface signaling assemblies
Werner Kühlbrandt (MPI for Biophysics): Membrane proteins: Structure and mechanisms
John Kuriyan, (UC Berkeley): Cellular signal transduction
Debora Marks(Harvard University): TBD
Jenny Martin (Griffith University): Antimicrobial drug design,
Naoko Mizuno (MPI for Biochemistry): TBD
Poul Nissen (Aarhus University): Membrane transporters in the brain,
Lori Passmore (LMB Cambridge): TBD
Michael Rossmann (Purdue University): The structure of the Zika virus
Michael Rout (The Rockefeller University: The nuclear pore complex,
Giovanna Scapin (Merck & Co): Structural Biology in Drug Discovery
Irmi Sinning (Heidelberg University): Protein targeting and membrane protein biogenesis,
Titia Sixma (NKI Amsterdam): Molecular mechanisms in carcinogenesis,
David Stuart (University of Oxford): Virus structure and vaccine design,
Sriram Subramaniam (NCI Bethesda): High resolution electron microscopy,
Alessandro Vannini (ICR London): TBD
Antoine van Oijnen (University of Wollongong): Single molecule biophysics,
Wei Yang (NIDDK Bethesda): DNA repair, replication and recombination,
Xiaodong Zhang (Imperial College London): DNA processing and damage response,
WORKSHOPS
Riccardo Pellarin (Pasteur Institute) Integrative Modeling Platform
Cornelius Gati (MRC) RELION
Randy Read (MRC) Validation/errors
Paul Emsley (MRC) COOT
Debbie Marks & Chris Sanders (Harvard) EV fold
Airlie McCoy (MRC) Solution and refinement of large complexes/low resolution systems
Ardan Patwardhan (EBI/PDBe) EMDB/EMPIAR: linking structural information from molecules to cells;
Giovanna Scapin
Principal Scientist
Structural Chemistry
Merck & Co., Inc.
2000 Galloping Hill Rd
K15-1800
Room B133C
Kenilworth NJ 07033
Phone +1 908 740 3632
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