I wouldn't touch this one with a ten foot pole because of all of the gunk floating around in Amniotic fluid that could be a potential interference
Dr. Alter
David Alter, MD DABCC
Clinical/Chemical Pathologist
Point of Care Testing-System Medical Director
Clinical Professor of Pathology MSU-CHM
Spectrum Health Regional Laboratory
35 Michigan Street
Grand Rapids MI 49503
616 267 2786
Clinical Pathology - "Knowledge, Communication and Diplomacy; not necessarily in that order."
"Knowledge speaks, but wisdom listens." Jimi Hendrix
From: Clinical biochemistry discussion list [mailto:[log in to unmask]] On Behalf Of MARTIN, Nick (ROYAL FREE LONDON NHS FOUNDATION TRUST)
Sent: Tuesday, November 15, 2016 9:11 AM
To: [log in to unmask]
Subject: Amniotic Fluid TFTs
Dear Mailbase
We have been contacted by an obstetrician wanting to measure TSH and T4 (free or total) in amniotic fluid to guide the intrauterine treatment of a foetus with a goitre. The published literature suggests that the T4 and TSH in the amniotic fluid reflect foetal production and these measurements would be useful. Has anyone validated their TSH and/or T4 assays for use in amniotic fluid or know of anywhere that has? This request is a new one for us and any advice would be greatly appreciated.
Many thanks
Nick
Nick Martin
Consultant Clinical Scientist and Deputy Director of the SAS Trace Element Service
Clinical Biochemistry
Imperial College Healthcare NHS Trust
London, UK
Tel: 02033133644
Email: [log in to unmask]<mailto:[log in to unmask]>
Email: [log in to unmask]<mailto:[log in to unmask]>
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