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Agreed Jonathan The 1999 WHO definition is attached and I doubt many people follow it to the letter. Eric From: Clinical biochemistry discussion list [mailto:[log in to unmask]] On Behalf Of Jonathan Kay Sent: Thursday, November 24, 2016 12:47 PM To: [log in to unmask] Subject: Re: Lucozade is changing What fraction of oral glucose tolerance tests have ever been done in compliance with the procedure used in the definition? Jonathan On 24 Nov 2016, at 09:33, David James <[log in to unmask]<mailto:[log in to unmask]>> wrote: Beta carotene safe except when taken in excess such that it increases hepatic stores of retinyl esters…..except when < about 18 montsh old before maturation of the carotene dioxygenase enzyme ☺ dj From: Clinical biochemistry discussion list [mailto:[log in to unmask]] On Behalf Of OCONNOR, John (ROYAL DEVON AND EXETER NHS FOUNDATION TRUST) Sent: 22 November 2016 17:10 To: [log in to unmask]<mailto:[log in to unmask]> Subject: Re: Lucozade is changing Gary Does that apply to the amount of beta carotene they use to colour it also? Perhaps we should throw in LFT’s at the same time as the glucose measurements :P) BW John From: Clinical biochemistry discussion list [mailto:[log in to unmask]] On Behalf Of Gary Woodward Sent: 22 November 2016 16:22 To: [log in to unmask]<mailto:[log in to unmask]> Subject: Re: Lucozade is changing Having worked for GSK in a past life (on Lucozade), I can’t say that their batch-to-batch control would stand up to clinical standards anyway (unless colour, taste and specific gravity are validated ways of calculating glucose content). Gary From: Clinical biochemistry discussion list [mailto:[log in to unmask]] On Behalf Of Colley, Michael Sent: 22 November 2016 16:10 To: [log in to unmask]<mailto:[log in to unmask]> Subject: Re: Lucozade is changing A quick calculation suggests that it’s still 113 ml of Polycal to provide 75 g anhydrous glucose equivalent. So, the sales of Lucozade should drop sharply. Michael This email is not personalised advice and does not constitute any recommendation to trade. Our research is designed for investors who are happy to make their own investment decisions. From: Clinical biochemistry discussion list [mailto:[log in to unmask]] On Behalf Of Colley, Michael Sent: 22 November 2016 10:00 To: [log in to unmask]<mailto:[log in to unmask]> Subject: Re: Lucozade is changing Lucozade has never been appropriate for GTTs, as the volume required has always exceeded that given in the protocol. The reduction in content means it’s even worse, as John points out. Try Polycal (I’m not sure if the composition is the same as when I did the original study in 1990 (!!!) but back then you needed 113 ml of Polycal solution). Michael From: Clinical biochemistry discussion list [mailto:[log in to unmask]]<mailto:[mailto:[log in to unmask]]> On Behalf Of OCONNOR, John (ROYAL DEVON AND EXETER NHS FOUNDATION TRUST) Sent: 21 November 2016 16:36 To: [log in to unmask]<mailto:[log in to unmask]> Subject: Lucozade is changing We heard a rumour that Lucozade composition is changing, its still widely used for identifying gestational diabetes through OGTT The message below suggests this is true, still plenty of time to think about it though. For 75g I work that out to be 950mls!! BW john From: LRS Consumer Care [mailto:[log in to unmask]]<mailto:[mailto:[log in to unmask]]> Sent: 21 November 2016 16:24 To: OCONNOR, John (ROYAL DEVON AND EXETER NHS FOUNDATION TRUST) Subject: [Case Number:56161:184810:40241] [Case Number:56161:184810:40241] Dear John, Thank you for your email regarding the sugar reduction in our drinks. The new recipes will start appearing on shelf from July 2017 and will have a 50% sugar reduction. All Lucozade Energy flavours will still contain at least 20g of glucose based carbohydrates per 250ml. In a 380ml bottle, there will be approximately 30g of glucose based carbohydrates. We are proactively informing all relevant associations like the NHS and Diabetic groups across the UK. I hope this answers your question, if you have any further questions please let us know. Kind regards, Jemini Consumer Care Department T: 0800 096 3666 [X] ________________________________ ******************************************************************************************************************** This message may contain confidential information. If you are not the intended recipient please inform the sender that you have received the message in error before deleting it. Please do not disclose, copy or distribute information in this e-mail or take any action in reliance on its contents: to do so is strictly prohibited and may be unlawful. Thank you for your co-operation. 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