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Optseq2 should be downloaded. Did you get it to download yet? If you need a more complicated design or want to compare other design matrices, you could use the following: M = C*inv(X'*X)*C'; eff = 1/trace(M); vrf = 1/mean(diag(M)); where C is your contrast of interest and X is the design matrix. Higher eff and vrf are better, but you still need to have an effect. A higher vrf is better if you expect smaller effects. For more details on design efficiency, see http://imaging.mrc-cbu.cam.ac.uk/imaging/DesignEfficiency Best, Donald Best Regards, Donald McLaren, PhD On Wed, Sep 21, 2016 at 3:27 AM, Alexandre Obert <[log in to unmask]> wrote: > Dear all, > > I would like to introduce jitters and to test the efficiency of my design > but I don't know which tool to use. > My first idea was to use optseq2, but I can't download it (probably a > server pb- maybe someone could send it to me?). > Is there any other tool that could help me? > > Regards, > > Alexandre >