Hello all,

I am analyzing functional connectivity data for 20 children. We are finding that the contrasts show activation outside of the standard brain after dual regression. An issue with registration, possibly?

This is my command for dual regression:

dual_regression GrouplevelnoFRA.gica/groupmelodic.ica/melodic_IC.nii.gz 1 GLM_20.mat GLM_20.con 5000 20_5000.dr 001A_filtered_func_data.nii.gz 003A_filtered_func_data.nii.gz 004A_filtered_func_data.nii.gz 005A_filtered_func_data.nii.gz 007A_filtered_func_data.nii.gz 019A_filtered_func_data.nii.gz 021A_filtered_func_data.nii.gz 022A_filtered_func_data.nii.gz 037A_filtered_func_data.nii.gz 041A_filtered_func_data.nii.gz 008A_filtered_func_data.nii.gz 011A_filtered_func_data.nii.gz 015A_filtered_func_data.nii.gz 027A_filtered_func_data.nii.gz 029A_filtered_func_data.nii.gz 035A_filtered_func_data.nii.gz 039A_filtered_func_data.nii.gz 044A_filtered_func_data.nii.gz 045A_filtered_func_data.nii.gz 048A_filtered_func_data.nii.gz

We are using a standard pediatric brain as the standard that is not from FSL and are performing dual regression at a 4mm voxel so that it runs faster.

Let me know if you have any tips or suggestions.

Thank you for your time and expertise.

Cheers,

Noelle Dalin