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Summary that I am going to use to justify buying MacOSX instead of Windows (in case this is of use to others): Not available in Windows: ADXV for looking at crystallographic diffraction images XDS and HKL2000 for crystallographic data processing (Auto)SHARP for phasing ARPWARP for automated model building (Auto)BUSTER for structure refinement Uppsala Software Factory programs (Mapman, etc.), manipulation of maps and PDB files Cryo-EM software (EMAN2, BSOFT) Available in Windows but with important limitations: Phenix (no MR-Rosetta, no parallelization) DIALS (no parallelization) Mark J van Raaij Dpto de Estructura de Macromoleculas Centro Nacional de Biotecnologia - CSIC calle Darwin 3 E-28049 Madrid, Spain tel. (+34) 91 585 4616 http://wwwuser.cnb.csic.es/~mjvanraaij