 |
 |
. . MEDICAL: DISEASES: ZIKA VIRUS : TREATMENT: Zika Treatable with Existing Drugs, Says Breakthrough Study Written by Catharine Paddock PhD Published: Tuesday 30 August 2016 Medical News Today (MNT) http://www.medicalnewstoday.com/articles/312596.php . . "We focused on compounds that have the shortest path to clinical use. This is a first step toward a therapeutic that can stop transmission of this disease." . One of the compounds he and his colleagues discovered is the basis for a drug called Niclosamide that is approved by the Food and Drug Administration (FDA). The drug is commonly used to treat tapeworm and animal studies show it is safe for use in pregnancy. . In theory, doctors could prescribe the drug today, but it needs to undergo tests to repurpose it as a treatment for Zika virus infection. . Earlier this year, members of the team had found a link between Zika and microcephaly - a severe birth defect where babies are born with a much smaller head and brain. This led to the search for drug compounds that might prevent the viral damage. . Repurposing screen sifted through 6,000 existing drugs For their new work, the team developed a drug repurposing screen, a relatively new method that researchers are using to speed up drug development. . snip . The two classes of compounds they identified are capable of protecting brain cells from cell death induced by Zika virus activity. . One class of compounds is antiviral in nature and stops the virus multiplying. . The other class of compounds is neuroprotective in nature and stops the virus carrying out cell-damaging "caspase-3 activity" in human cortical neural progenitors - precursors to brain cells in fetal development. . . The complete article may be read at the URL above. . . Sincerely, David Dillard Temple University (215) 204 - 4584 [log in to unmask] http://workface.com/e/daviddillard Net-Gold https://groups.io/g/Net-Gold http://groups.yahoo.com/group/net-gold http://listserv.temple.edu/archives/net-gold.html https://groups.io/org/groupsio/Net-Gold/archives http://net-gold.3172864.n2.nabble.com/ Temple University and Google Sites Research Guides AND Discussion Group Directory http://tinyurl.com/ngda2hk OR https://sites.google.com/site/researchguidesonsites/ RESEARCH PAPER WRITING http://guides.temple.edu/research-papers EMPLOYMENT http://guides.temple.edu/employment-guide INTERNSHIPS http://guides.temple.edu/employment-internships HOSPITALITY http://guides.temple.edu/hospitality-guide DISABILITIES AND EMPLOYMENT http://guides.temple.edu/c.php?g=134557 INDOOR GARDENING https://groups.io/g/indoor-gardening Educator-Gold http://groups.yahoo.com/group/Educator-Gold/ K12ADMINLIFE http://groups.yahoo.com/group/K12AdminLIFE/ PUBLIC HEALTH RESOURCES INCLUDING EBOLA http://guides.temple.edu/public-health-guide STATISTICS SOURCES RESEARCH GUIDE http://guides.temple.edu/statistics-sources Social Work and Social Issues Discussion Group https://groups.io/g/social-work Tourism Discussion Group https://groups.io/g/Tourism Digital Scholarship Discussion Group https://groups.io/g/DigitalScholarship/threads https://listserv.temple.edu/cgi-bin/wa?A0=DIGITAL-SCHOLARSHIP https://groups.yahoo.com/neo/groups/digital-scholarship/info https://digitalscholarshipandscholarlypublication.wordpress.com/ Copyright Research Guide Copyright, Intellectual Property and Plagiarism Sources http://guides.temple.edu/copyright-plagiarism Fair Use http://guides.temple.edu/fair-use Blog https://educatorgold.wordpress.com/ Articles by David Dillard https://sites.google.com/site/daviddillardsarticles/ Information Literacy (Russell Conwell Guide) http://tinyurl.com/78a4shn Nina Dillard's Photographs on Net-Gold http://www.flickr.com/photos/neemers/ Twitter: davidpdillard Temple University Site Map https://sites.google.com/site/templeunivsitemap/home Bushell, R. & Sheldon, P. (eds), Wellness and Tourism: Mind, Body, Spirit, Place, New York: Cognizant Communication Books. Wellness Tourism: Bibliographic and Webliographic Essay David P. Dillard http://tinyurl.com/o4pn4o9 Rail Transportation https://groups.io/org/groupsio/RailTransportation INDOOR GARDENING Improve Your Chances for Indoor Gardening Success http://tech.groups.yahoo.com/group/IndoorGardeningUrban/ SPORT-MED https://www.jiscmail.ac.uk/lists/sport-med.html http://groups.yahoo.com/group/sports-med/ http://listserv.temple.edu/archives/sport-med.html HEALTH DIET FITNESS RECREATION SPORTS TOURISM https://groups.yahoo.com/neo/groups/healthrecsport/info http://listserv.temple.edu/archives/health-recreation-sports-tourism.html . . Please Ignore All Links to JIGLU in search results for Net-Gold and related lists. The Net-Gold relationship with JIGLU has been terminated by JIGLU and these are dead links. http://groups.yahoo.com/group/Net-Gold/message/30664 http://health.groups.yahoo.com/group/healthrecsport/message/145 Temple University Listserv Alert : Years 2009 and 2010 Eliminated from Archives https://sites.google.com/site/templeuniversitylistservalert/ . .