For the record, ARIA is not to blame here. It's rather a Python/Shell issue. Python relies on the shell to expand environment variables. But some shells don't expand tilde (~) when quoted... Best, Benjamin On 05/09/16 14:51, Edith Gincel wrote: > Benjamin Bardiaux just gave me the answer... > aria doesn't like the "~/" instead of absolute paths.... > > anyway, thank you very much for your help > > Edith > -- --------------------------------------------- Dr Benjamin Bardiaux [log in to unmask] Unité de Bioinformatique Structurale CNRS UMR3528 - Institut Pasteur 25,28 rue du Docteur Roux 75015 Paris, France ---------------------------------------------