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That would be correct, T-shaped or edge to face From: CCP4 bulletin board [mailto:[log in to unmask]] On Behalf Of WENHE ZHONG Sent: Wednesday, 7 September 2016 3:08 p.m. To: [log in to unmask] Subject: [ccp4bb] Tryptophan-Adenine interaction: T-shaped stacking? Dear CCP4BB, One tryptophan residue (side chain) in my case regulates the binding of AMP. The attached figure representing the relative position of the tryptophan and AMP. I am not very familiar with the chemistry in terms of π-stacking. So I am wondering whether it is a T-shaped stacking interaction between the aromatic rings? Any thought? Thanks! Kind regards, Wenhe [cid:image001.png@01D2092D.B78E99C0]