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Dear SPMers, We performed an experiment on readers and pre-readers with speech and print conditions. On second level analysis we computed null conjunction for the 2 contrast in each group (one sample t-test) which produced significant activation in readers while not in pre-readers. However, when the paper was sent to review one of the reviewers wanted us “to compute the conjunction of print and speech on the first level and put these contrasts into a 2-sample t-test on the second-level”. However we came across some difficulties. If we save thresholded SPM map from each subject when performing null conjunction in SPM contrast manager and feed these maps to 2^nd level the model cannot be estimated and there is an error saying “there are no inmask voxels” (even though we used very lenient p<0.05 uncorrected threshold for the 1st level conjunction). Is there a better way of doing multisubject conjunction? Thank you in advance, Marek -- Marek Wypych PhD Laboratory of Brain Imaging (LOBI) Neurobiology Center Nencki Institute of Experimental Biology Pasteur 3, 02-093 Warsaw, Poland Tel.: +48 22 5892 550 http://lobi.nencki.gov.pl/