**Staff Scientist for cryo-electron microscopy**
Location:	Grenoble, France
Staff Category:	Staff Member
Contract Duration:	3 years
Grading:	8
Closing Date:	16 October 2016
Reference Number:	GR_00102

Job Description

The European Molecular Biology Laboratory (EMBL) is one of the highest ranked scientific research organisations in the world. The Headquarters Laboratory is located in Heidelberg (Germany), with additional sites in Grenoble (France), Hamburg (Germany), Hinxton (UK) and Monterotondo (Italy).

We wish to recruit an experienced and motivated scientist to join a team to establish and run a state-of-the-art cryo-EM facility for structural biology on the European Photon and Neutron (EPN) Campus in Grenoble. This is a Partnership for Structural Biology (PSB) project together with the European Synchrotron Radiation Facility (ESRF) and Institut de Biologie Structurale (IBS) and involves installation of a Titan Krios with K2 detector within the ESRF. This instrument, complemented by other electron microscopes on campus (e.g. Polar/K2 and F20 at IBS, T12 at EMBL), will be open for external user access mainly for high resolution data collection for 3D single particle reconstruction. The tasks of the successful candidate will be to

- participate in installation, commissioning and running of the ESRF cryo-EM facility
- help users in data collection and preliminary data analysis
- keep up-to-date processing software and hardware in collaboration with local IT staff
- implement or develop novel methods in cryo-EM (e.g. automation of sample handling) in collaboration with local engineers
- co-organise practical training in cryo-EM for internal and external users.
- contribute expertise to in house structural biology research projects in collaboration with EMBL Grenoble group leaders.
- liase with the electron microscopists at EMBL Heidelberg and Hamburg.

Qualifications and Experience

Applicants should have the following qualifications

- PhD degree in the physical or biological sciences
- Several years demonstrable experience in cryo-electron microscopy (including sample handling, data collection and image processing) as applied to structural biology
- Ability and desire to provide a high quality service to users
- Ability and desire to work in a collaborative international research environment together with scientists from collaborating EPN Campus institutes
- Good communication skills in English

EMBL is an inclusive, equal opportunity employer offering attractive conditions and benefits appropriate to an international research organisation with a very collaborative and family friendly atmosphere. We strongly encourage applications from female candidates with the relevant qualifications. The working language of the institute is English.

Application Instructions

Please apply online through

www.embl.org/jobs

Additional Information

Further information about this position can be obtained from the Head of Grenoble Outstation, Stephen
Cusack ([log in to unmask]). See also http://www.embl.fr

Please note that appointments on fixed term contracts can be renewed, depending on circumstances at the time of the review.