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You should average the the two runs before doing the group analysis.

Best Regards,
Donald McLaren, PhD


On Thu, Jun 16, 2016 at 2:19 PM, Malak abu shakra <[log in to unmask]
> wrote:

> Dr. McLaren,
>
> Please forgive my dwelling on this issue but one last related question:
> the same stress test that I used for each alcohol and placebo day contained
> two runs. In order to assess the main effect of personality, sex and their
> interaction on each of the two rounds under a single condition (alcohol or
> placebo), should I also perform two separate full factorial models, one for
> each run or is it legit to just do one that combines the two?
>
> Thank you again for the very clear responses and helpful answers.
>
> Malak
>
>
> On Wed, Jun 15, 2016 at 7:37 AM, Donald McLaren <[log in to unmask]>
> wrote:
>
>> Yes.
>>
>> On Jun 15, 2016, at 2:08 AM, Malak abu shakra <[log in to unmask]>
>> wrote:
>>
>> Dear Dr. McLaren,
>>
>> Thank you ! am I to understand, based on your response, that running a
>> full factorial twice, once for alcohol and another placebo would be the
>> valid way to go?
>>
>> Malak
>>
>> On Mon, Jun 13, 2016 at 1:46 PM, MCLAREN, Donald <
>> [log in to unmask]> wrote:
>>
>>> No. You can't use a full factorial model for looking at the
>>> between-subject effects if you have repeated model. What you need to do is
>>> to run a model(s) without repeated measures to look at between-subject
>>> effects.
>>>
>>>
>>> Best Regards,
>>> Donald McLaren, PhD
>>>
>>>
>>> On Mon, Jun 13, 2016 at 12:49 PM, malak abu shakra <
>>> [log in to unmask]> wrote:
>>>
>>>> Dear SPMers,
>>>>
>>>> I have a quick question re. how much information to model using the
>>>> full factorial design: my study included one within-subject factor (2
>>>> levels, alcohol vs placebo conditions) and two between-subject factors
>>>> (risk profile: 2 levels; sex, 2 levels).
>>>>
>>>> I am aware that a flexible factorial should be used to compare
>>>> within-subject effects and full factorial for between-subject differences.
>>>> What I'm not quite sure of is the following:
>>>>
>>>> Even though I do not my full factorial model to look at within-subject
>>>> differences, would it be statistically preferable that I still feed the
>>>> model ALL the information obtained for subjects on both the placebo and
>>>> alcohol conditions? (meaning, condition would be added as a third factor in
>>>> my full factorial, with non-independent observations and equal variance).
>>>> Or, would it alternatively be better if I repeat the same analysis twice,
>>>> feeding it the placebo information the first time and alcohol information
>>>> the second?
>>>>
>>>> Thank you very much !
>>>>
>>>>
>>>> --
>>>> Malak Abu Shakra    Doctoral Student
>>>> Clinical Psychology
>>>> Psychology Dept.   Robert O. Pihl Lab
>>>> McGill University
>>>> 1205 Dr. Penfield Avenue
>>>> Stewart Biology Building - Room W8/37
>>>> Montreal, Quebec, H3A 1B1
>>>> Canada
>>>>
>>>>
>>>
>>
>>
>> --
>> Malak Abu Shakra    Doctoral Candidate
>> Clinical Psychology
>> Psychology Dept.   Robert O. Pihl Lab
>> McGill University
>> 1205 Dr. Penfield Avenue
>> Stewart Biology Building - Room W8/37
>> Montreal, Quebec, H3A 1B1
>> Canada
>>
>> "The most erroneous stories are those we think we know best - and
>> therefore never scrutinize or question".
>> Stephen Jay Gould -
>>
>>
>>
>
>
> --
> Malak Abu Shakra    Doctoral Candidate
> Clinical Psychology
> Psychology Dept.   Robert O. Pihl Lab
> McGill University
> 1205 Dr. Penfield Avenue
> Stewart Biology Building - Room W8/37
> Montreal, Quebec, H3A 1B1
> Canada
>
> "The most erroneous stories are those we think we know best - and
> therefore never scrutinize or question".
> Stephen Jay Gould -
>
>
>