Hi Walid,Please, see below:On 31 July 2016 at 06:10, Walid Y. <[log in to unmask]> wrote:Hello FSL experts,I am trying to create a design where i want to check the difference between 2 groups patient and control (TBSS/Glm).However i want 1 EV to be a covariate of no interest and two of interest.Currently I’m at:EVs:G1 G2 Age Variable1 Variable21 0 demeand demeand demeand0 1 demeand demeand demeandContrasts:C1 1 -1 0 0 0C2 -1 1 0 0 0C3 0 0 0 1 0C4 0 0 0 0 1C5 0 0 0 0.5 0.5Contrasts C1-C4 are fine, and the interpretation as indicated below is correct. C5 can only be used if the measurement units of variables 1 and 2 are the same and their sum is meaningful. I am not sure what is your hypothesis for C5 but perhaps an F-test with C3 and C4 (for any effect) or a conjunction (for an effect in both) could be better/more informative.I want to test the difference between groups 1 and group 2 taking age as a nuisance covariate and variable 1 and variable 2 covariates of interest.C3 is the effect of V1 between groups 1 & 2 (taking age and V2 as nuisance covariates)C4 is the effect of V2 between groups 1 & 2 (taking age and V1 as nuisance covariates)C5 is the effect of both V1 and V2 between groups 1 & 2 taking age as nuisance covariate.Incase i want to check the effect of V1 with age as a nuisance covariance ONLY, then i will remove V2 from EVs and run it as:G1 G2 Age Variable11 0 demeand demeand0 1 demeand demeandContrasts:C1 1 -1 0 0C2 -1 1 0 0C3 0 0 0 1 <= V1 with age as a nuisance covariance ONLYThis is fine.All the best,AndersonIs my design correct? Thank you for your advice.Best regards,
Walid