Dear Christian, Could you please provide help with CAT12? Segmentation keeps crashing with one particular T1 image although it worked fine with many other images. SPM12's Segmentation function, on the other hand, has no problem with this image. Below is the terminal output with the "warning" lines highlighted. Would you be able to advise how to get around this problem? Many thanks, Kie Woo CAT12 r938: ./Image.nii ------------------------------------------------------------------------ SANLM denoising (NCstr=Inf): 295s APP: Rough bias correction: Initialize 9s Estimate background 8s Initial correction 19s Refine background 11s Final correction 16s Background correction 1s Final scaling 4s 68s Coarse affine registration 12s Affine registration 15s SPM preprocessing 1: 192s SPM preprocessing 2: 242s Global intensity correction: 34s SANLM noise correction: 5s Local adaptive segmentation (LASstr=0.50): Prepare maps 2s Prepare partitions 3s Prepare segments 6s Estimate local tissue thresholds 312s SANLM noise correction for LAS: 8s 331s ROI segmentation (partitioning): Atlas -> subject space 6s Major structures 1s Ventricle detection 3s NO WMH detection (to noisy ~0.18) 0s Closing of deep structures 1s Side alignment 3s Final corrections 3s 17s Skull-stripping using graph-cut (gcutstr=0.50): WM initialisation [@Warning: WARNING: cat_vol_morph - lab - no object!]@ [@> In cat_vol_morph at 119 In cat_main_gcut at 93 In cat_main at 845 In cat_run_job at 541 In cat_run_newcatch at 13 In cat_run>run_job at 246 In cat_run at 154 In matlabbatch/private/cfg_run_cm at 29 In cfg_util>local_runcj at 1688 In cfg_util at 959 In spm_jobman>fill_run_job at 458 In spm_jobman at 247]@ 2s 2s Amap using initial SPM12 segmentations (MRF filter strength 0.07): MRF priors: alpha 1.000 0.000 0.000 Final Mean*Std: 0.663*0.299 -0.340*0.112 -0.340*0.030 Weighted MRF beta -nan @@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@@ 1s Final cleanup (gcutstr=0.50): Level 1 cleanup (ROI estimation) 1s Level 1 cleanup (brain masking) [@Warning: WARNING: cat_vol_morph - lab - no object!]@ [@> In cat_vol_morph at 119 In cat_vol_morph at 107 In cat_main_cleanup at 58 In cat_main at 965 In cat_run_job at 541 In cat_run_newcatch at 13 In cat_run>run_job at 246 In cat_run at 154 In matlabbatch/private/cfg_run_cm at 29 In cfg_util>local_runcj at 1688 In cfg_util at 959 In spm_jobman>fill_run_job at 458 In spm_jobman at 247]@ ------------------------------------------------------------------------ CAT Preprocessing error: MATLAB:dimagree: ./Image.nii ------------------------------------------------------------------------ Matrix dimensions must agree. ------------------------------------------------------------------------ 59 - cat_main_cleanup 965 - cat_main 541 - cat_run_job 13 - cat_run_newcatch 246 - run_job 154 - cat_run 29 - cfg_run_cm 1688 - local_runcj 959 - cfg_util 458 - fill_run_job 247 - spm_jobman ------------------------------------------------------------------------ Print 'Graphics' figure to: /Path/report/catreport_Image.pdf Failed 'CAT12: Segmentation' Error using & Matrix dimensions must agree. In file "/SPMpath/spm/toolboxes/CAT/cat12_v938/cat_main_cleanup.m" (???), function "cat_main_cleanup" at line 59. In file "/SPMpath/spm/toolboxes/CAT/cat12_v938/cat_main.m" (v928), function "cat_main" at line 965. In file "/SPMpath/spm/toolboxes/CAT/cat12_v938/cat_run_job.m" (v936), function "cat_run_job" at line 541. In file "/SPMpath/spm/toolboxes/CAT/cat12_v938/cat_run_newcatch.m" (???), function "cat_run_newcatch" at line 13. In file "/SPMpath/spm/toolboxes/CAT/cat12_v938/cat_run.m" (v936), function "run_job" at line 246. In file "/SPMpath/spm/toolboxes/CAT/cat12_v938/cat_run.m" (v936), function "cat_run" at line 154. The following modules did not run: Failed: CAT12: Segmentation >> >>