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Hi, You are right - this is a factor that reduces the object voxel size compared to the image voxel size. We have found from our simulations that it is important to have at least 2 for a static image and at least 6 for an image where motion is being simulated, in order to reduce the approximation error appropriately. If the factor is too small then certain artefacts can be seen in the simulations. However, the default values (2 and 6), which are dynamically changed if you add/remove motion from the simulation, work well and you can use these values without further alteration. All the best Mark From: FSL - FMRIB's Software Library <[log in to unmask]<mailto:[log in to unmask]>> on behalf of David Parker <[log in to unmask]<mailto:[log in to unmask]>> Reply-To: FSL - FMRIB's Software Library <[log in to unmask]<mailto:[log in to unmask]>> Date: Tuesday, 17 May 2016 19:00 To: "[log in to unmask]<mailto:[log in to unmask]>" <[log in to unmask]<mailto:[log in to unmask]>> Subject: [FSL] POSSUM Slice resampling factor Hello everyone, I'm attempting to run some Possum simulations, and I'm wondering what that "Object slice resampling factor", under the "Pulse sequence tab" is. My guess it that it's the factor with which it upsamples the brain object, is that correct? Would there be any reason to make this higher than 1 or 2?