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I would not recommend smoothing before ICA+FIX. Peace, Matt. On 5/5/16, 11:22 AM, "FSL - FMRIB's Software Library on behalf of Sara De Simoni" <[log in to unmask] on behalf of [log in to unmask]> wrote: >Dear FSL users & experts, > >I have a question regarding cleaning data with FIX - > >My understanding is that smoothing of functional data is recommended >prior to FIX to increase SNR (my data does not have high spatial/temporal >resolution). > >However I would like to use SPM DARTEL tools to normalise my functional >data. This step incorporates smoothing and does not work properly if >smoothing is not used. > >I don't want to apply smoothing to my data twice so my question is this: > >Can I clean non-smoothed data with the noise components classified as >such by using the same smoothed data? > >Thanks for your help with this! > >Sara